Interest is growing in the relocalization of staple crops, including wheat, in western Washington (WWA), a nontraditional wheat-growing area. Commercial bakers are potentially important food chain intermediaries in the case of relocalized wheat production. We conducted a mail survey of commercial bakers in WWA to assess their interest in sourcing wheat/flour from WWA, identify the characteristics of bakeries most likely to purchase wheat/flour from WWA, understand the factors important to bakers in purchasing regionally produced wheat/flour, and identify perceived barriers to (...) making such purchases. Sixty-one percent of survey respondents were interested in purchasing WWA wheat/flour. Bakers who used retail strategies to market their products were more likely to be interested in WWA wheat/flour compared to those not using retail methods. Bakers’ current purchases of Washington wheat/flour were not related to their interest in purchasing WWA flour. The most important factors bakers would consider in purchasing regionally produced wheat/flour were consistency of flour quality, quality of flour, and reliability of supply. Cost was the most frequently mentioned barrier to the purchase of regionally produced wheat/flour. Our results are relevant for other areas attempting to reconnect grain producers, commercial bakers, and consumers in mutually beneficial ways. (shrink)

Nanomedicine is yielding new and improved treatments and diagnostics for a range of diseases and disorders. Nanomedicine applications incorporate materials and components with nanoscale dimensions where novel physiochemical properties emerge as a result of size-dependent phenomena and high surface-to-mass ratio. Nanotherapeutics and in vivo nanodiagnostics are a subset of nanomedicine products that enter the human body. These include drugs, biological products, implantable medical devices, and combination products that are designed to function in the body in ways unachievable at larger scales. (...) Nanotherapeutics andin vivonanodiagnostics incorporate materials that are engineered at the nanoscale to express novel properties that are medicinally useful. These nanomedicine applications can also contain nanomaterials that are biologically active, producing interactions that depend on biological triggers. Examples include nanoscale formulations of insoluble drugs to improve bioavailability and pharmacokinetics, drugs encapsulated in hollow nanoparticles with the ability to target and cross cellular and tissue membranes and to release their payload at a specific time or location, imaging agents that demonstrate novel optical properties to aid in locating micrometastases, and antimicrobial and drug-eluting components or coatings of implantable medical devices such as stents. (shrink)

Jones's system of constraints promises interesting insights into the typology of kin term systems. Three problems arise: (1) the conflation of categories with algorithms that assign them threatens to weaken the typological predictions; (2) OT-type constraints have little psychological plausibility; (3) the conflation of kin-term systems and kinship systems may underplay the “utility function” character of real kinship in action.

Durkheim's The Rules of Sociological Method has never enjoyed the same reputation as his major books, in part because the book is uncongenial to standard interpretations of Durkheim. In particular, its attacks on teleology do not fit his reputation as a functionalist The papers in this special issue address the work historically. Both Porter and Stedman Jones deal with aspects of the context in which Durkheim worked and transformed. Schmaus and Nemedi deal with problems of interpreting Durkheim's development, and (...) Platt discusses the reception of The Rules. The papers shed light on such important questions as the meaning of Durkheim's slogan “society is made of representations.” Durkheim, it appears, was not only what would now be called a constructionist, he went on to ask whether the fact that constructions are real in their consequences did not imply the reality causal reality of constructions and, therefore, a specific kind of “social realism.” The problem The Rules poses, of what is the fundamental stuff of society, is “classic” in significance, and Durkheim's answer is classically radical. (shrink)

The starting-point of this paper is one of the most disastrous pieces of advocacy in modern legal history. In October 1960, Penguin Books were prosecuted under Section 2 of the 1959 Obscene Publications Act for publishing an unexpurgated edition ofLady Chatterley's Lover.On the first day of the trial, Mr. Mervyn Griffith-Jones, Senior Treasury Counsel, did his best to wreck his case on the strength of one remark. He had previously tried to show that he was himself a man of (...) the world: ‘Let me emphasize this on behalf of the prosecution: do not approach this matter in any priggish, high-minded, super-correct, mid-Victorian manner’. He now proceeded to work this out in practice: ‘Would you approve of your young sons, young daughters—because girls can read as well as boys—reading this book? Is it a book that you would have lying around in your own house? Is it even a book that you would wish your wife or your servants to read?’. (shrink)

A dazzling insight into what gives meaning to our life and to us as a species. What makes us human? From Professor Brian Cox on the particles of dust that make us, to Caitlin Moran on the joy of Friday nights, and A C Grayling on how we express ourselves through culture: this illuminating book shares over 100 mind-expanding answers to that question. We all want to understand our place in the universe and find a sense of purpose in the (...) life. This book will help the reader navigate that journey with the help of leading names from the worlds of literature, history, philosophy, politics, sport, comedy and popular culture. Originally broadcast as a popular feature on the Jeremy Vine Show, What Makes Us Human? includes short essays from: Andrew Marr, Carlo Rovelli, Justin Welby, Marian Keyes, Alain de Botton, Robert Webb, Richard Dawkins, Stephen Fry, and many more"--Publisher's description. (shrink)

If we think about comedy in terms of stock characters, Shakespeare provides some startling examples. Here, for instance, are two hypothetical casts: A jealous husband, a chaste wife, an irascible father, a clever malicious servant, a gullible friend, a bawdy witty maid; A pair of lovers, their irascible fathers, a bawdy serving woman, a witty friend, a malicious friend, a kindly foolish priest. Both of these groups represent recognizable comic configurations, though in fact they are also the casts of Othello (...) and Romeo and Juliet. Being able to see them in this light, I think, reveals something important about how both these tragedies work. Much of their dramatic force derives from the way they continually tempt us with comic possibilities. We are told in a prologue that Romeo and Juliet are star-crossed, but if inevitability is a requisite of tragedy, neither play will qualify for the genre: they are the most iffy dramas in the Shakespearean canon. At innumerable points in both plays, had anything happened differently, the tragic catastrophe would have been averted. Othello particularly teases the audience in this way—as the famous story about the man who leapt from his seat, furious at the impending murder of Desdemona, and shouted "You fool, can't you see she's innocent?" reveals. The story is no doubt apocryphal , but the point is that it is unique to this play: there are no similar tales of spectators leaping up to rescue Cordelia, to save Gloucester from blinding, to dash the asp from Cleopatra's hand. Stephen Orgel, professor of English at Johns Hopkins University, is the author of The Jonsonian Masque, The Illusion of Power, and the coauthor of Inigo Jones. The editor of Jonson's Complete Masques and of Jonson's Selected Masques , he is currently writing a book on the idea of theatrical genres in the Renaissance. (shrink)

Among the works of Aelius Aristides is preserved an address to an unnamed ‘king’. The prevailing view in this century has been that it is addressed to a third-century emperor, and was attributed to Aristides in error. In an article published in 1972 , 134–52), I argued that the speech was genuine, and was delivered by Aristides in 144 before Antoninus Pius. In a recent article in this journal , 172–97), Stephen A. Stertz has undertaken to rebut this view, (...) and advances a novel one: the speech is a school exercise written in the third or perhaps the fourth century, and does not refer to any particular ‘king’, not even necessarily a Roman emperor. Rather than attempt to answer all of Stertz's arguments, I have selected as samples one each from several diverse fields. Manuscript tradition. In his first paragraph, Stertz suggests that the manuscript tradition of the Eis basilea itself impugns its authenticity. ‘The oration is entitled єς βασιλέα in three manuscripts and єς τόν ατοκρτορα in another. It has been pointed out that in the former group of manuscripts the title is not preceded by the words ριστεδου λόγος, thus casting doubt on Aristidean authorship' . The accompanying footnote refers to Keil's apparatus ad loc, and the reader might infer that this argument is borrowed from Aristides’ foremost editor. What Keil said was: ‘Titulus ες βασιλα STC : єς τòν ατοκρτορα U et in indice D m recentiss.’. (shrink)

In this paper, I present and criticize two highly influential anti-skeptical proposals inspired by Wittgenstein’s (1969) remarks on ‘hinges’, namely Pritchard’s ‘hinge commitment strategy’ (2012, forthcoming a, forthcoming b) and Moyal-Sharrock ‘non epistemic strategy’ (2004,2005). I argue that both these proposals fail to represent a valid response to skeptical worries. Furthermore, I argue that following Wittgenstein’s analogy between ‘hinges’ and ‘rules of grammar’ we should be able to get rid of Cartesian skeptical scenarios as nonsensical, even if apparently intelligible, combination (...) of signs excluded from our epistemic practices. (shrink)

William James is famous for his investigations of the “Varieties of Religious Experience” in which people encounter (what they take to be) the divine. But in his essay, “On a Certain Blindness in Human Beings,” his interest is in our experiences, not of anything purportedly supernatural, but of one another. He thinks we need to cultivate the capacity to apprehend the intrinsic value of others, even and especially of strangers. We do so in experiences of the wonder and beauty of (...) our fellow citizens, and of our harmony with them. Democratic societies require a sense of attraction to one another’s form of life if they are to inspire shared commitments to public goods. Whereas we shouldn’t reject the political significance of aversion, contestation, and dissonance, these negative attitudes do not suffice. Sustaining democratic engagement requires attractive attitudes, and among these are the wonder, beauty, and harmony that James promotes. (shrink)

Moral horror is an extreme emotional response to that which violates things we regard as sacred. In Robert Merrihew Adams's view, horror is a response to badness and not to wrongness, and so one could properly regard some actions as horrible but not wrong. In contrast, I argue that horror, when directed toward actions, is only appropriate for wrong actions. The reason is that horror involves moral disgust, and agents who committed a horrible action would have self-disgust, that is, they (...) would be repulsive to themselves. I argue, with reference to killing in combat and in self-defense, that those who have done no wrong should not be in such a state. (shrink)

The selective connections that nerve cells make to each other and to effector and receptor cells outside the nervous system are essential to organized behavior. The retinotectal projection has been used frequently in the experimental investigation of how such patterned sets of connections are formed. This article traces the evolution of some of the dominant experimental paradigms and concepts that have resulted in the currently accepted rules underlying the retinotectal map.

The public debate over the ethics of cloning has been as thoughtful, and as sensational, as any in bioethics in recent years. Two essays bring us up to date. —Ed.

Jotkowitz, Glick, and Gesundheit (2008) rightly critique Manninen (2006) for an errant analysis of the Groningen protocol. However, they draw conclusions about the protocol itself that are not justified. Because of the nature of the care of infants, the Groningen protocol doesn't break new ethical ground. We already have to treat infants without direct access to their autonomous preferences or values; therefore, we are already making the decisions that Jotkowitz, Glick, and Gesundheit argue we are beginning to take once active (...) euthanasia of infants is allowed. (shrink)

An anxious resident paged ethics at 2:00 a.m. His patient, Mr. M, a twenty‐nine‐year‐old man with a history of multiple substance abuse, was in the hospital after cardiac arrest and lack of cerebral perfusion. Sadly, the young man probably met the criteria for brain death, but the final apnea test to confirm the diagnosis could not be done for another forty‐eight to seventy‐two hours because the Klonopin in his system might confound the results. The resident's concern, however, addressed a request (...) made by the patient's mother for a sperm harvest. The patient's mother maintained that her son had said he wanted to give her grandchildren. She wished to harvest sperm from him for a future use with an as‐yet‐to‐be‐determined surrogate mother. (shrink)

The internet is widely used for health information and support, often by vulnerable people. Internet-based research raises both familiar and new ethical problems for researchers and ethics committees. While guidelines for internet-based research are available, it is unclear to what extent ethics committees use these. Experience of gaining research ethics approval for a UK study (SharpTalk), involving internet-based discussion groups with young people who self-harm and health professionals is described. During ethical review, unsurprisingly, concerns were raised about the vulnerability of (...) potential participants. These were dominated by the issue of anonymity, which also affected participant safety and consent. These ethical problems are discussed, and our solutions, which included: participant usernames specific to the study, a closed website, private messaging facilities, a direct contact email to researchers, information about forum rules displayed on the website, a ‘report’ button for participants, links to online support, and a discussion room for forum moderators. This experience with SharpTalk suggests that an approach to ethics, which recognises the relational aspects of research with vulnerable people, is particularly useful for internet-based health research. The solutions presented here can act as guidance for researchers developing proposals and for ethics committees reviewing them. (shrink)

A compelling investigation into one of the most coveted and cherished ideals, "Wisdom" also chronicles the efforts of modern science to penetrate the mysterious nature of this timeless virtue.

This is a biography of the works of Richard Price, 1723-1791, one of the leading radical intellectuals of the late-18th century. By profession a dissenting minister, he was also a mathematician, a political pamphleteer, particularly on the American and French Revolutions, and a moral philosopher.

Hintikka has criticized psychologists for "hasty epistemologizing," which he takes to be an unwarranted transfer of ideas from psychology (a discipline dealing with questions of fact) into epistemology (a discipline dealing with questions of method and theory). Hamlyn argues, following Hintikka, that Gibson's theory of perception is an example of such an inappropriate transfer, especially insofar as Hamlyn feels Gibson does not answer several important questions. However, Gibson's theory does answer the relevant questions, albeit in a new and radical way, (...) which suggests that the alleged distinction between psychology and epistemology is suspect. In fact, contrary to Hintikka and Hamlyn's claims, Gibson's theory of perception appears to be a valuable source of epistemological as well as psychological ideas. (shrink)

Autonomous vehicles have the potential to save tens of thousands of lives, but legal and social barriers may delay or even deter manufacturers from offering fully automated vehicles and thereby cost lives that otherwise could be saved. Moral philosophers use “thought experiments” to teach us about what ethics might say about the ethical behavior of AVs. If a manufacturer designing an AV decided to make what it believes is an ethical choice to save a large group of lives by steering (...) away from the large group towards a single individual, could the manufacturer be liable to that single individual? I believe the answer is yes. This article discusses famous “trolley problem” thought experiments in moral philosophy, which news articles have recently applied to AVs. After establishing a hypothetical case, applying product liability law to AV behavior may show a way, in some jurisdictions, that will permit a manufacturer to implement an ethical choice without triggering liability, but liability risk remains. I then turn to possible traditional defenses to see if they prevent liability for a manufacturer making what it believes is an ethical design choice—necessity, defense of self, and the sudden emergency doctrine. None of them provides an effective defense. Under current law, maximizing collision avoidance appears to minimize legal risk. I conclude that the only way to provide effective protection to a manufacturer seeking to implement ethical choices about AV behavior is through special legislation or regulation. (shrink)

presents a puzzle as to whether Aristotle views morally virtuous activity as happiness, as book 1 seems to indicate, or philosophical contemplation as happiness, as book 10 seems to indicate. The most influential attempts to resolve this issue have been either monistic or inclusivist. According to the monists, happiness consists exclusively of contemplation. According to the inclusivists, contemplation is one constituent of happiness, but morally virtuous activity is another. In this essay I will examine influential defenses of monism. Finding these (...) accounts superior to inclusivism, but still deficient, I will present and defend a dualistic account of happiness in which two different types of happiness, one divine and one human, are present in Nicomachean Ethics. When Aristotle commends contemplation as a happiness that humans can attain, he is careful to specify that this activity corresponds to a capacity (nous) that is not, properly speaking, human, even though humans can exercise it. Contemplation, the divine good, is the highest good that humans can obtain, but it is not the characteristic human good. The characteristic human good corresponds to the specifically and merely human function, which is an activity of the compound of human reason and emotions. (shrink)

Jecker, et al., argue against rejecting a location for an international bioethics conference based on a “litmus test” for several reasons, ranging from the practical to the theoretical. However, th...

This Comment argues that Stephen Bush's critique of Georges Bataille's meditative practice fails to recognize how the disruption of the self, and the challenge to goal-oriented activity that comprise the heart of that practice, serve as an ethical limit that protects against sadistic and violent engagement with the world. The ethical disposition fostered by Bataille's practice is a dissolution of the self. In this reply to Kent Brintnall's response to my essay on Georges Bataille and the ethics of ecstasy, (...) I explore two primary questions: whether instrumentalization is inherently violent and non-instrumentalization is inherently non-violent, and whether there is a way to intervene in the world that avoids both "apathetic disengagement" and domination. I endorse the view that instrumentalization can be good as well as bad, and I suggest that it is possible to strive to intervene in the world without striving to master it. I make reference to Sarah Coakley as a Christian theologian who advances particular practices that aim for non-dominating intervention in theworld. (shrink)

Response to ’African vital force and the permissibility of euthanasia’ Lougheed’s discussion of vital force in metaphysics in African thought and its implications for euthanasia is not only of interest for African philosophy, but also for bioethics within and outside of Africa. A debate exists as to whether or not there is, or should be, a uniquely African bioethics,1 but equally worthwhile is using the insights of African philosophy to develop bioethics generally speaking, whether African, Western or all-inclusive. The inclusion (...) of African philosophical thought into Western bioethical thought can expand the useful application of bioethical theories outside of the largely Western conceptual areas they now employ and can help resolve some of the challenges that Western bioethics has addressing justice and the moral value of community and family connections. However, the argument that vital force/vitalism is always incompatible with voluntary active euthanasia is an unhelpful inclusion of African thought into bioethics. The concern is not that Lougheed is mistaken; vitalism, understood as treating life as having the highest value, probably does make physician aid in dying by active euthanasia (or assisted suicide) always impermissible. The problem is that this is well-trodden ground in Western bioethics, which has been …. (shrink)

William James argued for a philosophy of democracy and pluralism that advocates individual and collective responsibility for our social arrangements, our morality, and our religion. In James' view, democracy resides first and foremost not in governmental institutions or in procedures such as voting, but rather in the characteristics of individuals, and in qualities of mind and conduct. It is a philosophy for social change, counselling action and hope despite the manifold challenges facing democratic politics, and these issues still resonate strongly (...) today. In this book, Stephen Bush explores how these themes connect to James' philosophy of religion, his moral thought, his epistemology, his psychology, and his metaphysics. His fresh and original study highlights the relevance of James' thought to modern debates, and will appeal to scholars and students of moral and political philosophy. (shrink)

Winner of the Gustave O. Arlt Award in the HumanitiesThree understandings of the nature of religion--religion as experience, symbolic meaning, and power--have dominated scholarly discussions, in succession, for the past hundred years. Proponents of each of these three approaches have tended to downplay, ignore, or actively criticize the others. But why should the three approaches be at odds? Religion as it is practiced involves experiences, meanings, and power, so students of religion should attend to all three. Furthermore, theorists of religion (...) should have an account that carefully conceptualizes all three aspects, without regarding any of them as more basic than the others.Visions of Religion provides just such an account. Stephen S. Bush examines influential proponents of the three visions, arguing that each approach offers substantial and lasting contributions to the study of religion, although each requires revision.Bush rehabilitates the concepts of experience and meaning, two categories that are much maligned these days. In doing so, he shows the extent to which these categories are implicated in matters of social power. As for power, the book argues that the analysis of power requires attention to meaning and experience.Visions of Religion accomplishes all this by articulating a social practical theory of religion that can account for all three aspects, even as it incorporates them into a single theoretical framework. (shrink)

As Nair-Collins and Joffe note, the concern that our tests for brain death do not successfully show that all brain functions have stopped is not new (Nair-Collins and Joffe 2023). As our abilities...

In this reply to Kent Brintnall's response to my essay on Georges Bataille and the ethics of ecstasy, I explore two primary questions: whether instrumentalization is inherently violent and non-instrumentalization is inherently non-violent, and whether there is a way to intervene in the world that avoids both “apathetic disengagement” and domination. I endorse the view that instrumentalization can be good as well as bad, and I suggest that it is possible to strive to intervene in the world without striving to (...) master it. I make reference to Sarah Coakley as a Christian theologian who advances particular practices that aim for non-dominating intervention in theworld. (shrink)

Since 1991, over half the states have enacted laws that restrict or prohibit insurers’ use of genetic information in pricing, issuing, or structuring health insurance. Wisconsin was the first state to do so, in 1991, followed by Ohio in 1993, California and Colorado in 1994, and then several more states a year in each of the next five years. Similar legislation has been pending in Congress for several years. Also, a 1996 federal law known as the Health Insurance Portability and (...) Accountability Act prohibits group health insurers from applying “preexisting condition” exclusions to genetic conditions that are indicated solely by genetic tests and not by any actual symptoms. (shrink)